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Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients: a prospective single center observational study

BACKGROUND: Several studies have indicated that commonly used piperacillin-tazobactam (TZP) and meropenem (MEM) dosing regimens lead to suboptimal plasma concentrations for a range of pharmacokinetic/pharmacodynamic (PK/PD) targets in intensive care unit (ICU) patients. These targets are often based...

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Detalles Bibliográficos
Autores principales: De Corte, Thomas, Verhaeghe, Jarne, Dhaese, Sofie, Van Vooren, Sarah, Boelens, Jerina, G. Verstraete, Alain, Stove, Veronique, Ongenae, Femke, De Bus, Liesbet, Depuydt, Pieter, Van Hoecke, Sofie, J. De Waele, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148758/
https://www.ncbi.nlm.nih.gov/pubmed/37119362
http://dx.doi.org/10.1186/s13613-023-01129-6