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Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation

The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify antitumor potency remains unexplored. Herein, we demonstrate that nanoparticle-mediated transi...

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Detalles Bibliográficos
Autores principales: Li, Ting, Jiang, Shuhui, Zhang, Ying, Luo, Jie, Li, Ming, Ke, Hengte, Deng, Yibin, Yang, Tao, Sun, Xiaohui, Chen, Huabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148815/
https://www.ncbi.nlm.nih.gov/pubmed/37120615
http://dx.doi.org/10.1038/s41467-023-38128-x