Cargando…
Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation
The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However, precisely dismantling self-defenses to amplify antitumor potency remains unexplored. Herein, we demonstrate that nanoparticle-mediated transi...
Autores principales: | Li, Ting, Jiang, Shuhui, Zhang, Ying, Luo, Jie, Li, Ming, Ke, Hengte, Deng, Yibin, Yang, Tao, Sun, Xiaohui, Chen, Huabing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148815/ https://www.ncbi.nlm.nih.gov/pubmed/37120615 http://dx.doi.org/10.1038/s41467-023-38128-x |
Ejemplares similares
-
Blockade of TRPV channels by intracellular spermine
por: Maksaev, Grigory, et al.
Publicado: (2023) -
ThermoTRP Channels in Nociceptors: Taking a Lead from Capsaicin Receptor TRPV1
por: Mandadi, Sravan, et al.
Publicado: (2008) -
Molecular basis for heat desensitization of TRPV1 ion channels
por: Luo, Lei, et al.
Publicado: (2019) -
Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold
por: Cao, Xu, et al.
Publicado: (2014) -
The heat is on! TRPV1 channels and resistance artery myogenic tone
por: Jackson, William F.
Publicado: (2022)