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Positive feedback induces switch between distributive and processive phosphorylation of Hog1

Cellular decision making often builds on ultrasensitive MAPK pathways. The phosphorylation mechanism of MAP kinase has so far been described as either distributive or processive, with distributive mechanisms generating ultrasensitivity in theoretical analyses. However, the in vivo mechanism of MAP k...

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Detalles Bibliográficos
Autores principales: Mosbacher, Maximilian, Lee, Sung Sik, Yaakov, Gilad, Nadal-Ribelles, Mariona, de Nadal, Eulàlia, van Drogen, Frank, Posas, Francesc, Peter, Matthias, Claassen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148820/
https://www.ncbi.nlm.nih.gov/pubmed/37120434
http://dx.doi.org/10.1038/s41467-023-37430-y