Targeting fatty acid oxidation via Acyl-CoA binding protein hinders glioblastoma invasion

The diffuse nature of Glioblastoma (GBM) tumors poses a challenge to current therapeutic options. We have previously shown that Acyl-CoA Binding Protein (ACBP, also known as DBI) regulates lipid metabolism in GBM cells, favoring fatty acid oxidation (FAO). Here we show that ACBP downregulation resul...

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Detalles Bibliográficos
Autores principales: Duman, Ceren, Di Marco, Barbara, Nevedomskaya, Ekaterina, Ulug, Berk, Lesche, Ralf, Christian, Sven, Alfonso, Julieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148872/
https://www.ncbi.nlm.nih.gov/pubmed/37120445
http://dx.doi.org/10.1038/s41419-023-05813-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148872/
https://www.ncbi.nlm.nih.gov/pubmed/37120445
http://dx.doi.org/10.1038/s41419-023-05813-0

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