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Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space

Inflammasomes are multi-protein complexes and play a crucial role in host defense against pathogens. Downstream inflammatory responses through inflammasomes are known to be related to the oligomerization degree of ASC specks, but the detailed mechanism still remains unexplored. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Yu, Tae-Geun, Cha, Jeong Seok, Kim, Gijeong, Sohn, Yoo-Kyoung, Yoo, Youngki, Kim, Uijin, Song, Ji-Joon, Cho, Hyun-Soo, Kim, Hak-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148886/
https://www.ncbi.nlm.nih.gov/pubmed/37120628
http://dx.doi.org/10.1038/s41420-023-01438-6