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Functional genomics in stroke: current and future applications of iPSCs and gene editing to dissect the function of risk variants
Stroke is an important disease with unmet clinical need. To uncover novel paths for treatment, it is of critical importance to develop relevant laboratory models that may help to shed light on the pathophysiological mechanisms of stroke. Induced pluripotent stem cells (iPSCs) technology has enormous...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148993/ https://www.ncbi.nlm.nih.gov/pubmed/37120540 http://dx.doi.org/10.1186/s12872-023-03227-6 |