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Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis

BACKGROUND: Tumour necrosis factor (TNF) is a pleiotropic cytokine and master regulator of the immune system. It acts through two receptors resulting in often opposing biological effects, which may explain the lack of therapeutic potential obtained so far in multiple sclerosis (MS) with non-receptor...

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Detalles Bibliográficos
Autores principales: Fiedler, Timon, Fairless, Richard, Pichi, Kira, Fischer, Roman, Richter, Fabian, Kontermann, Roland E., Pfizenmaier, Klaus, Diem, Ricarda, Williams, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149004/
https://www.ncbi.nlm.nih.gov/pubmed/37122019
http://dx.doi.org/10.1186/s12974-023-02784-z