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Inhibition of nucleotide biosynthesis disrupts lipid accumulation and adipogenesis

Energy balance and nutrient availability are key determinants of cellular decisions to remain quiescent, proliferate, or differentiate into a mature cell. After assessing its environmental state, the cell must rewire its metabolism to support distinct cellular outcomes. Mechanistically, how metaboli...

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Detalles Bibliográficos
Autores principales: Shinde, Abhijit B., Nunn, Elizabeth R., Wilson, Genesis A., Chvasta, Mathew T., Pinette, Julia A., Myers, Jacob W., Peck, Sun H., Spinelli, Jessica B., Zaganjor, Elma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149209/
https://www.ncbi.nlm.nih.gov/pubmed/36963490
http://dx.doi.org/10.1016/j.jbc.2023.104635