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The Batten disease protein CLN3 is important for stress granules dynamics and translational activity

The assembly of membrane-less organelles such as stress granules (SGs) is emerging as central in helping cells rapidly respond and adapt to stress. Following stress sensing, the resulting global translational shutoff leads to the condensation of stalled mRNAs and proteins into SGs. By reorganizing c...

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Detalles Bibliográficos
Autores principales: Relton, Emily L., Roth, Nicolas J., Yasa, Seda, Kaleem, Abuzar, Hermey, Guido, Minnis, Christopher J., Mole, Sara E., Shelkovnikova, Tatyana, Lefrancois, Stephane, McCormick, Peter J., Locker, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149212/
https://www.ncbi.nlm.nih.gov/pubmed/36965618
http://dx.doi.org/10.1016/j.jbc.2023.104649