Cargando…

ATP modulates self-perpetuating conformational conversion generating structurally distinct yeast prion amyloids that limit autocatalytic amplification

Prion-like self-perpetuating conformational conversion of proteins into amyloid aggregates is associated with both transmissible neurodegenerative diseases and non-Mendelian inheritance. The cellular energy currency ATP is known to indirectly regulate the formation, dissolution, or transmission of a...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahapatra, Sayanta, Sarbahi, Anusha, Punia, Neha, Joshi, Ashish, Avni, Anamika, Walimbe, Anuja, Mukhopadhyay, Samrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149227/
https://www.ncbi.nlm.nih.gov/pubmed/36990219
http://dx.doi.org/10.1016/j.jbc.2023.104654