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Machine learning-assisted medium optimization revealed the discriminated strategies for improved production of the foreign and native metabolites

The composition of medium components is crucial for achieving the best performance of synthetic construction in genetically engineered cells. Which and how medium components determine the performance, e.g., productivity, remain poorly investigated. To address the questions, a comparative survey with...

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Detalles Bibliográficos
Autores principales: Aida, Honoka, Uchida, Keisuke, Nagai, Motoki, Hashizume, Takamasa, Masuo, Shunsuke, Takaya, Naoki, Ying, Bei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149329/
https://www.ncbi.nlm.nih.gov/pubmed/37138901
http://dx.doi.org/10.1016/j.csbj.2023.04.020