Phosphodiesterase type 10A inhibitor attenuates lung fibrosis by targeting myofibroblast activation

Pulmonary fibrosis (PF) is a fatal and irreversible respiratory disease accompanied by excessive fibroblast activation. Previous studies have suggested that cAMP signaling pathway and cGMP-PKG signaling pathway are continuously down-regulated in lung fibrosis, whereas PDE10A has a specifically expre...

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Detalles Bibliográficos
Autores principales: Li, Ya-Jun, Shi, Jian-Rong, Li, Shu-Chan, Wang, Lu-Ming, Dhar, Rana, Li, Ning, Cao, Xin-Wei, Li, Zi-Gang, Tang, Hui-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149334/
https://www.ncbi.nlm.nih.gov/pubmed/37138780
http://dx.doi.org/10.1016/j.isci.2023.106586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149334/
https://www.ncbi.nlm.nih.gov/pubmed/37138780
http://dx.doi.org/10.1016/j.isci.2023.106586

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