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Analysis of monoclonal immunoglobulins from bone marrow plasma cells using immunopurification and LC-MS

INTRODUCTION: Clonal plasma cells secrete immunoglobulins, each with the exact same amino acid sequence, that are referred to as monoclonal immunoglobulins. The monoclonal heavy chain and light chain secreted from clonal plasma cells have the same molecular mass prior to the addition of post-transla...

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Detalles Bibliográficos
Autores principales: Barnidge, David R., Dispenzieri, Angela, Jevremovic, Dragan, Murray, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149385/
https://www.ncbi.nlm.nih.gov/pubmed/37138663
http://dx.doi.org/10.1016/j.jmsacl.2023.04.001