Western Diet Causes Heart Failure With Reduced Ejection Fraction and Metabolic Shifts After Diastolic Dysfunction and Novel Cardiac Lipid Derangements

Western diet (WD) impairs glucose tolerance and cardiac lipid dynamics, preceding heart failure with reduced ejection fraction (HFrEF) in mice. Unlike diabetic db/db mice with high cardiac triglyceride (TG) and rapid TG turnover, WD mice had high TG but slowed turnover, reducing lipolytic PPAR⍺ acti...

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Detalles Bibliográficos
Autores principales: Maurya, Santosh K., Carley, Andrew N., Maurya, Chandan K., Lewandowski, E. Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149654/
https://www.ncbi.nlm.nih.gov/pubmed/37138801
http://dx.doi.org/10.1016/j.jacbts.2022.10.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149654/
https://www.ncbi.nlm.nih.gov/pubmed/37138801
http://dx.doi.org/10.1016/j.jacbts.2022.10.009

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