Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model

Enterovirus A71 (EV-A71) can elicit a wide variety of human diseases such as hand, foot, and mouth disease and severe or fatal neurological complications. It is not clearly understood what determines the virulence and fitness of EV-A71. It has been observed that amino acid changes in the receptor bi...

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Detalles Bibliográficos
Autores principales: Aknouch, Ikrame, García-Rodríguez, Inés, Giugliano, Francesca Paola, Calitz, Carlemi, Koen, Gerrit, van Eijk, Hetty, Johannessson, Nina, Rebers, Sjoerd, Brouwer, Lieke, Muncan, Vanesa, Stittelaar, Koert J., Pajkrt, Dasja, Wolthers, Katja C., Sridhar, Adithya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149690/
https://www.ncbi.nlm.nih.gov/pubmed/37138595
http://dx.doi.org/10.3389/fmicb.2023.1045587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149690/
https://www.ncbi.nlm.nih.gov/pubmed/37138595
http://dx.doi.org/10.3389/fmicb.2023.1045587

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