α/Sulfono-γ-AA peptide hybrids agonist of GLP-1R with prolonged action both in vitro and in vivo

Peptides are increasingly important resources for biological and therapeutic development, however, their intrinsic susceptibility to proteolytic degradation represents a big hurdle. As a natural agonist for GLP-1R, glucagon-like peptide 1 (GLP-1) is of significant clinical interest for the treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Yan, Lee, Candy, Sang, Peng, Amso, Zaid, Huang, David, Zhong, Weixia, Gu, Meng, Wei, Lulu, Nguyen-Tran, Vân T.B., Zhang, Jingyao, Shen, Weijun, Cai, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149899/
https://www.ncbi.nlm.nih.gov/pubmed/37139407
http://dx.doi.org/10.1016/j.apsb.2022.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149899/
https://www.ncbi.nlm.nih.gov/pubmed/37139407
http://dx.doi.org/10.1016/j.apsb.2022.10.014

Ejemplares similares