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Building on the backbone of CD47-based therapy in cancer: Combination strategies, mechanisms, and future perspectives
Described as a “don't eat me” signal, CD47 becomes a vital immune checkpoint in cancer. Its interaction with signal regulatory protein alpha (SIRPα) prevents macrophage phagocytosis. In recent years, a growing body of evidences have unveiled that CD47-based combination therapy exhibits a superi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149906/ https://www.ncbi.nlm.nih.gov/pubmed/37139405 http://dx.doi.org/10.1016/j.apsb.2022.12.016 |