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5-Demethylnobiletin mediates cell cycle arrest and apoptosis via the ERK1/2/AKT/STAT3 signaling pathways in glioblastoma cells

5-Demethylnobiletin is the active ingredient in citrus polymethoxyflavones that could inhibit the proliferation of several tumor cells. However, the anti-tumor effect of 5-Demethylnobiletin on glioblastoma and the underlying molecular mechanisms are remains unknown. In our study, 5-Demethylnobiletin...

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Detalles Bibliográficos
Autores principales: Zhang, Xuehua, Zhao, Leilei, Xiao, Jinlong, Wang, Yudi, Li, Yunmeng, Zhu, Chaoqun, Zhang, He, Zhang, Yurui, Zhu, Xiao, Dong, Yucui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149914/
https://www.ncbi.nlm.nih.gov/pubmed/37139163
http://dx.doi.org/10.3389/fonc.2023.1143664