Enhanced protein synthesis is a defining requirement for neonatal B cell development

The LIN28B RNA binding protein exhibits an ontogenically restricted expression pattern and is a key molecular regulator of fetal and neonatal B lymphopoiesis. It enhances the positive selection of CD5+ immature B cells early in life through amplifying the CD19/PI3K/c-MYC pathway and is sufficient to...

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Detalles Bibliográficos
Autores principales: Åkerstrand, Hugo, Boldrin, Elena, Montano, Giorgia, Vanhee, Stijn, Olsson, Karin, Krausse, Niklas, Vergani, Stefano, Cieśla, Maciej, Bellodi, Cristian, Yuan, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149930/
https://www.ncbi.nlm.nih.gov/pubmed/37138883
http://dx.doi.org/10.3389/fimmu.2023.1130930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149930/
https://www.ncbi.nlm.nih.gov/pubmed/37138883
http://dx.doi.org/10.3389/fimmu.2023.1130930

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