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Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19

INTRODUCTION: Mannose-binding lectin (MBL) promotes opsonization, favoring phagocytosis and activation of the complement system in response to different microorganisms, and may influence the synthesis of inflammatory cytokines. This study investigated the association of MBL2 gene polymorphisms with...

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Detalles Bibliográficos
Autores principales: Queiroz, Maria Alice Freitas, Santiago, Angélica Menezes, Brito, Wandrey Roberto dos Santos, Pereira, Keise Adrielle Santos, de Brito, William Botelho, Torres, Maria Karoliny da Silva, Lopes, Jeferson da Costa, dos Santos, Erika Ferreira, da Costa, Flávia Póvoa, de Sarges, Kevin Matheus Lima, Cantanhede, Marcos Henrique Damasceno, de Brito, Mioni Thieli Figueiredo Magalhães, da Silva, Andréa Luciana Soares, Leite, Mauro de Meira, Viana, Maria de Nazaré do Socorro de Almeida, Rodrigues, Fabíola Brasil Barbosa, da Silva, Rosilene, Viana, Giselle Maria Rachid, Chaves, Tânia do Socorro Souza, Veríssimo, Adriana de Oliveira Lameira, Carvalho, Mayara da Silva, Henriques, Daniele Freitas, dos Santos, Carla Pinheiro, Nunes, Juliana Abreu Lima, Costa, Iran Barros, Amoras, Ednelza da Silva Graça, Lima, Sandra Souza, Cayres-Vallinoto, Izaura Maria Vieira, Brasil-Costa, Igor, Quaresma, Juarez Antônio Simões, Falcão, Luiz Fábio Magno, dos Santos, Eduardo José Melo, Vallinoto, Antonio Carlos Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149935/
https://www.ncbi.nlm.nih.gov/pubmed/37138871
http://dx.doi.org/10.3389/fimmu.2023.1151058