Exploring the impact of clonal definition on B-cell diversity: implications for the analysis of immune repertoires

The adaptive immune system has the extraordinary ability to produce a broad range of immunoglobulins that can bind a wide variety of antigens. During adaptive immune responses, activated B cells duplicate and undergo somatic hypermutation in their B-cell receptor (BCR) genes, resulting in clonal fam...

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Detalles Bibliográficos
Autores principales: Pelissier, Aurelien, Luo, Siyuan, Stratigopoulou, Maria, Guikema, Jeroen E. J., Rodríguez Martínez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150052/
https://www.ncbi.nlm.nih.gov/pubmed/37138881
http://dx.doi.org/10.3389/fimmu.2023.1123968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150052/
https://www.ncbi.nlm.nih.gov/pubmed/37138881
http://dx.doi.org/10.3389/fimmu.2023.1123968

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