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Expression of non-phosphorylatable S5A-L-plastin exerts phenotypes distinct from L-plastin deficiency during podosome formation and phagocytosis

Introduction: The actin cytoskeleton remodels to enable diverse processes essential to immunity, such as cell adhesion, migration and phagocytosis. A panoply of actin-binding proteins regulate these rapid rearrangements to induce actin-based shape changes and to generate force. L-plastin (LPL) is a...

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Detalles Bibliográficos
Autores principales: Lin, Xue, Krishnamoorthy, Praveen, Walker, Emma C., Joshi, Hemant, Morley, Sharon Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150066/
https://www.ncbi.nlm.nih.gov/pubmed/37138794
http://dx.doi.org/10.3389/fcell.2023.1020091