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Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome

The congenital short QT syndrome (SQTS) is a rare condition characterized by abbreviated rate-corrected QT (QTc) intervals on the electrocardiogram and by increased susceptibility to both atrial and ventricular arrhythmias and sudden death. Although mutations to multiple genes have been implicated i...

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Detalles Bibliográficos
Autores principales: Hancox, J. C., Du, C. Y., Butler, A., Zhang, Y., Dempsey, C. E., Harmer, S. C., Zhang, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150212/
https://www.ncbi.nlm.nih.gov/pubmed/37122211
http://dx.doi.org/10.1098/rstb.2022.0165