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Late sodium current in synergism with Ca(2+)/calmodulin-dependent protein kinase II contributes to β-adrenergic activation-induced atrial fibrillation

Atrial fibrillation (AF) is frequently associated with β-adrenergic stimulation, especially in patients with structural heart diseases. The objective of this study was to determine the synergism of late sodium current (late I(Na)) and Ca(2+)/calmodulin-dependent protein kinase (CaMKII)-mediated arrh...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyan, Ren, Lu, Yu, Shandong, Li, Gang, He, Pengkang, Yang, Qiaomei, Wei, Xiaohong, Thai, Phung N., Wu, Lin, Huo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150221/
https://www.ncbi.nlm.nih.gov/pubmed/37122215
http://dx.doi.org/10.1098/rstb.2022.0163