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BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma

PURPOSE: BRD9 is a defining component of the noncanonical SWI/SNF complex, which regulates gene expression by controlling chromatin dynamics. Although recent studies have found an oncogenic role for BRD9 in multiple cancer types including multiple myeloma, its clinical significance and oncogenic mec...

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Detalles Bibliográficos
Autores principales: Kurata, Keiji, Samur, Mehmet K., Liow, Priscilla, Wen, Kenneth, Yamamoto, Leona, Liu, Jiye, Morelli, Eugenio, Gulla, Annamaria, Tai, Yu-Tzu, Qi, Jun, Hideshima, Teru, Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150249/
https://www.ncbi.nlm.nih.gov/pubmed/36780189
http://dx.doi.org/10.1158/1078-0432.CCR-22-3668