Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity

[Image: see text] Brevicidine and laterocidine are macrocyclic lipodepsipeptides with selective activity against Gram-negative bacteria, including colistin-resistant strains. Previously, the macrocyclic core of these peptides was thought essential for antibacterial activity. In this study, we show t...

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Detalles Bibliográficos
Autores principales: Ballantine, Ross D., Al Ayed, Karol, Bann, Samantha J., Hoekstra, Michael, Martin, Nathaniel I., Cochrane, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150354/
https://www.ncbi.nlm.nih.gov/pubmed/37071814
http://dx.doi.org/10.1021/acs.jmedchem.3c00308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150354/
https://www.ncbi.nlm.nih.gov/pubmed/37071814
http://dx.doi.org/10.1021/acs.jmedchem.3c00308

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