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Enhanced Antifungal Activity of Amphotericin B Bound to Albumin: A “Trojan Horse” Effect of the Protein

[Image: see text] Amphotericin B (AmB) is a life-saving and widely used antifungal antibiotic, but its therapeutic applicability is limited due to severe side effects. Here, we report that the formulation of the drug based on a complex with albumin (BSA) is highly effective against Candida albicans...

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Detalles Bibliográficos
Autores principales: Grela, Ewa, Stączek, Sylwia, Nowak, Monika, Pawlikowska-Pawlega, Bozena, Zdybicka-Barabas, Agnieszka, Janik, Sebastian, Cytryńska, Małgorzata, Grudzinski, Wojciech, Gruszecki, Wieslaw I., Luchowski, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150355/
https://www.ncbi.nlm.nih.gov/pubmed/37071547
http://dx.doi.org/10.1021/acs.jpcb.3c01168