Dietary tryptophan deficiency promotes gut RORγt(+) Treg cells at the expense of Gata3(+) Treg cells and alters commensal microbiota metabolism

Micronutrient deficiency is a major cause of disease throughout the world. Yet, how perturbations influence the immune-microbiome interface remains poorly understood. Here, we report that loss of dietary tryptophan (Trp) reshapes intestinal microbial communities, including the depletion of probiotic...

Descripción completa

Detalles Bibliográficos
Autores principales: Rankin, Lucille C., Kaiser, Katherine A., Santos-Alexis, Kenia de los, Park, Heekuk, Anne-Catrin, Uhlemann, Gray, Daniel H.D., Arpaia, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150404/
https://www.ncbi.nlm.nih.gov/pubmed/36840944
http://dx.doi.org/10.1016/j.celrep.2023.112135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150404/
https://www.ncbi.nlm.nih.gov/pubmed/36840944
http://dx.doi.org/10.1016/j.celrep.2023.112135

Ejemplares similares