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Dietary tryptophan deficiency promotes gut RORγt(+) Treg cells at the expense of Gata3(+) Treg cells and alters commensal microbiota metabolism
Micronutrient deficiency is a major cause of disease throughout the world. Yet, how perturbations influence the immune-microbiome interface remains poorly understood. Here, we report that loss of dietary tryptophan (Trp) reshapes intestinal microbial communities, including the depletion of probiotic...
Autores principales: | Rankin, Lucille C., Kaiser, Katherine A., Santos-Alexis, Kenia de los, Park, Heekuk, Anne-Catrin, Uhlemann, Gray, Daniel H.D., Arpaia, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150404/ https://www.ncbi.nlm.nih.gov/pubmed/36840944 http://dx.doi.org/10.1016/j.celrep.2023.112135 |
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