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Centrosome-dependent microtubule modifications set the conditions for axon formation

Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is unclear. Here, via high-resolution microscopy, we show that early developing neurons have fewer somatic acetylated MTs restricted near the ce...

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Detalles Bibliográficos
Autores principales: Meka, Durga Praveen, Kobler, Oliver, Hong, Shuai, Friedrich, Carina Meta, Wuesthoff, Souhaila, Henis, Melad, Schwanke, Birgit, Krisp, Christoph, Schmuelling, Nessa, Rueter, René, Ruecker, Tabitha, Betleja, Ewelina, Cheng, Tao, Mahjoub, Moe R., Soba, Peter, Schlüter, Hartmut, Fornasiero, Eugenio F., de Anda, Froylan Calderon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150443/
https://www.ncbi.nlm.nih.gov/pubmed/35443171
http://dx.doi.org/10.1016/j.celrep.2022.110686