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Centrosome-dependent microtubule modifications set the conditions for axon formation
Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is unclear. Here, via high-resolution microscopy, we show that early developing neurons have fewer somatic acetylated MTs restricted near the ce...
Autores principales: | Meka, Durga Praveen, Kobler, Oliver, Hong, Shuai, Friedrich, Carina Meta, Wuesthoff, Souhaila, Henis, Melad, Schwanke, Birgit, Krisp, Christoph, Schmuelling, Nessa, Rueter, René, Ruecker, Tabitha, Betleja, Ewelina, Cheng, Tao, Mahjoub, Moe R., Soba, Peter, Schlüter, Hartmut, Fornasiero, Eugenio F., de Anda, Froylan Calderon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150443/ https://www.ncbi.nlm.nih.gov/pubmed/35443171 http://dx.doi.org/10.1016/j.celrep.2022.110686 |
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