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TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer

BACKGROUND: Ovarian cancer (OC) is known for exhibiting low response rates to immune checkpoint inhibitors that activate T cells. However, immunotherapies that activate B cells have not yet been extensively explored and may be a potential target, as B cells that secrete immunoglobulins have been ass...

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Detalles Bibliográficos
Autores principales: Zorea, Jonathan, Motro, Yair, Mazor, Roei D., Carmi, Yifat Koren, Shulman, Ziv, Mahajna, Jamal, Moran-Gilad, Jacob, Elkabets, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150478/
https://www.ncbi.nlm.nih.gov/pubmed/37121997
http://dx.doi.org/10.1186/s13046-023-02680-7