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Effects of a peripherally acting µ-opioid receptor antagonist for the prevention of recurrent acute pancreatitis: study protocol for an investigator-initiated, randomized, placebo-controlled, double-blind clinical trial (PAMORA-RAP trial)

BACKGROUND: Acute and chronic pancreatitis constitute a continuum of inflammatory disease of the pancreas with an increasing incidence in most high-income countries. A subset of patients with a history of pancreatitis suffer from recurrence of acute pancreatitis attacks, which accelerate disease pro...

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Detalles Bibliográficos
Autores principales: Cook, Mathias E., Knoph, Cecilie S., Fjelsted, Camilla A., Frøkjær, Jens B., Bilgrau, Anders E., Novovic, Srdan, Jørgensen, Maiken Thyregod, Mortensen, Michael B., Nielsen, Liv B. J., Hadi, Amer, Berner-Hansen, Mark, Rutkowski, Wiktor, Vujasinovic, Miroslav, Löhr, Matthias, Drewes, Asbjørn M., Olesen, Søren S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150502/
https://www.ncbi.nlm.nih.gov/pubmed/37127657
http://dx.doi.org/10.1186/s13063-023-07287-z