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High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats

Lead (Pb) is a known environmental risk factor in the etiology of Alzheimer’s disease (AD). The existing reports suggest that Pb exposure increases beta-amyloid (Aβ) levels in brain tissues and cerebrospinal fluid (CSF) and facilitates the formation of amyloid plaques, which is a pathological hallma...

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Detalles Bibliográficos
Autores principales: Liu, Luke L., Shen, Xiaoli, Gu, Huiying, Zhao, Gang, Du, Yansheng, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150519/
https://www.ncbi.nlm.nih.gov/pubmed/37122007
http://dx.doi.org/10.1186/s12987-023-00432-5