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Esculetin releases maturation arrest and induces terminal differentiation in leukemic blast cells by altering the Wnt signaling axes

BACKGROUND: The “Differentiation therapy” has been emerging as a promising and more effective strategy against acute leukemia relapses. OBJECTIVE: In extension to the revolutionising therapeutic outcomes of All Trans Retinoic Acid (ATRA) to induce terminal differentiation of Acute Promyelocytic Leuk...

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Detalles Bibliográficos
Autores principales: Mathur, Ankit, Gangwar, Aman, Saluja, Daman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150528/
https://www.ncbi.nlm.nih.gov/pubmed/37127581
http://dx.doi.org/10.1186/s12885-023-10818-1