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Activation of ACLY by SEC63 deploys metabolic reprogramming to facilitate hepatocellular carcinoma metastasis upon endoplasmic reticulum stress

BACKGROUND: Tumor cells display augmented capability to maintain endoplasmic reticulum (ER) homeostasis and hijack ER stress pathway for malignant phenotypes under microenvironmental stimuli. Metabolic reprogramming is a well-known hallmark for tumor cells to provide specific adaptive traits to the...

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Detalles Bibliográficos
Autores principales: Hu, Chenyu, Xin, Zechang, Sun, Xiaoyan, Hu, Yang, Zhang, Chunfeng, Yan, Rui, Wang, Yuying, Lu, Min, Huang, Jing, Du, Xiaojuan, Xing, Baocai, Liu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150531/
https://www.ncbi.nlm.nih.gov/pubmed/37122003
http://dx.doi.org/10.1186/s13046-023-02656-7