Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TBNC) is an aggressive breast cancer subtype with a poor prognosis. Shugoshin-1 (SGO1) protects chromatids from early separation. Previous studies from our group have demonstrated that transient SGO1 downregulation suppresses early stages of metastasis (the...

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Detalles Bibliográficos
Autores principales: Jusino, Shirley, Rivera-Rivera, Yainyrette, Chardón-Colón, Camille, Rodríguez-Rodríguez, Patricia C., Román-González, Janeishly, Juliá-Hernández, Valeria S., Isidro, Angel, Mo, Qianxing, Saavedra, Harold I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150544/
https://www.ncbi.nlm.nih.gov/pubmed/37122033
http://dx.doi.org/10.1186/s13008-023-00088-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150544/
https://www.ncbi.nlm.nih.gov/pubmed/37122033
http://dx.doi.org/10.1186/s13008-023-00088-5

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