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PI3K Functions Downstream of Cdc42 to Drive Cancer phenotypes in a Melanoma Cell Line

Rho proteins are part of the Ras superfamily, which function to modulate cytoskeletal dynamics including cell adhesion and motility. Recently, an activating mutation in Cdc42, a Rho family GTPase, was found in a patient sample of melanoma. Previously, our work had shown the PI3K was important downst...

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Detalles Bibliográficos
Autores principales: Poku, Rosemary, Amissah, Felix, Alan, Jamie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150613/
https://www.ncbi.nlm.nih.gov/pubmed/37114375
http://dx.doi.org/10.1080/21541248.2023.2202612