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PI3K Functions Downstream of Cdc42 to Drive Cancer phenotypes in a Melanoma Cell Line
Rho proteins are part of the Ras superfamily, which function to modulate cytoskeletal dynamics including cell adhesion and motility. Recently, an activating mutation in Cdc42, a Rho family GTPase, was found in a patient sample of melanoma. Previously, our work had shown the PI3K was important downst...
Autores principales: | Poku, Rosemary, Amissah, Felix, Alan, Jamie K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150613/ https://www.ncbi.nlm.nih.gov/pubmed/37114375 http://dx.doi.org/10.1080/21541248.2023.2202612 |
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