Pro- and anti-tumour activities of CD146/MCAM in breast cancer result from its heterogeneous expression and association with epithelial to mesenchymal transition

CD146, also known as melanoma cell adhesion molecule (MCAM), is expressed in numerous cancers and has been implicated in the regulation of metastasis. We show that CD146 negatively regulates transendothelial migration (TEM) in breast cancer. This inhibitory activity is reflected by a reduction in MC...

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Detalles Bibliográficos
Autores principales: Mannion, Aarren J., Odell, Adam F., Baker, Syed Murtuza, Matthews, Laura C., Jones, Pamela F., Cook, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150653/
https://www.ncbi.nlm.nih.gov/pubmed/37138793
http://dx.doi.org/10.3389/fcell.2023.1129015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150653/
https://www.ncbi.nlm.nih.gov/pubmed/37138793
http://dx.doi.org/10.3389/fcell.2023.1129015

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