Colony-Stimulating Factor-1 Receptor Inhibition Transiently Attenuated the Peripheral Immune Response to Experimental Traumatic Brain Injury

To investigate microglial mechanisms in central and peripheral inflammation after experimental traumatic brain injury (TBI), we inhibited the colony-stimulating factor-1 receptor (CSF-1R) with PLX5622 (PLX). We hypothesized that microglia depletion would attenuate central inflammation acutely with n...

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Detalles Bibliográficos
Autores principales: Giordano, Katherine R., Saber, Maha, Green, Tabitha R.F., Rojas-Valencia, Luisa M., Ortiz, J. Bryce, Murphy, Sean M., Lifshitz, Jonathan, Rowe, Rachel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150725/
https://www.ncbi.nlm.nih.gov/pubmed/37139183
http://dx.doi.org/10.1089/neur.2022.0092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150725/
https://www.ncbi.nlm.nih.gov/pubmed/37139183
http://dx.doi.org/10.1089/neur.2022.0092

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