AS-605240 Blunts Osteoporosis by Inhibition of Bone Resorption

BACKGROUND: Osteoporosis is a metabolic bone disease. Osteoclasts are significantly involved in the pathogenesis of osteoporosis. AS-605240 (AS) is a small molecule PI3K-γ inhibitor and is less toxic compared to pan-PI3K inhibitors. AS also exerts multiple biological effects including anti-inflammat...

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Detalles Bibliográficos
Autores principales: Sun, Jiacheng, Cai, Guoping, Shen, Jinlong, Cheng, Pu, Zhang, Jiapeng, Jiang, Dengteng, Xu, Xianquan, Lu, Fangying, Chen, Lihua, Chen, Haixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150757/
https://www.ncbi.nlm.nih.gov/pubmed/37138583
http://dx.doi.org/10.2147/DDDT.S403231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150757/
https://www.ncbi.nlm.nih.gov/pubmed/37138583
http://dx.doi.org/10.2147/DDDT.S403231

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