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AS-605240 Blunts Osteoporosis by Inhibition of Bone Resorption

BACKGROUND: Osteoporosis is a metabolic bone disease. Osteoclasts are significantly involved in the pathogenesis of osteoporosis. AS-605240 (AS) is a small molecule PI3K-γ inhibitor and is less toxic compared to pan-PI3K inhibitors. AS also exerts multiple biological effects including anti-inflammat...

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Detalles Bibliográficos
Autores principales:	Sun, Jiacheng, Cai, Guoping, Shen, Jinlong, Cheng, Pu, Zhang, Jiapeng, Jiang, Dengteng, Xu, Xianquan, Lu, Fangying, Chen, Lihua, Chen, Haixiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150757/ https://www.ncbi.nlm.nih.gov/pubmed/37138583 http://dx.doi.org/10.2147/DDDT.S403231

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