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Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis

PURPOSE: Our study aims to reveal the pharmacological mechanism of Astragaloside IV in the treatment of pulmonary fibrosis(PF) through network pharmacology and experimental validation. METHODS: We first determined the in vivo anti-pulmonary fibrosis effect of Astragaloside IV by HE, MASSON staining,...

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Detalles Bibliográficos
Autores principales: Yuan, Su, Zuo, Biao, Zhou, Si-Cong, Wang, Meng, Tan, Kai-Yue, Chen, Zhi-Wei, Cao, Wen-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150770/
https://www.ncbi.nlm.nih.gov/pubmed/37138582
http://dx.doi.org/10.2147/DDDT.S404710