Endoplasmic Reticulum Stress and the Lysosomal Pathway Play Crucial Roles in the Progression of βB2-Crystallin Mutation-Induced Congenital Cataracts in Mice

PURPOSE: Congenital cataract is a major cause of visual impairment and childhood blindness; however, its underlying mechanism remains unclear. Here, we aimed to identify the roles of endoplasmic reticulum stress (ERS), lysosomal pathway, and lens capsule fibrosis during the progression of βB2-crysta...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Wei, Yang, Weimin, Zhang, Xinyu, Deng, Xiaoqian, Chen, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150832/
https://www.ncbi.nlm.nih.gov/pubmed/37103007
http://dx.doi.org/10.1167/iovs.64.4.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150832/
https://www.ncbi.nlm.nih.gov/pubmed/37103007
http://dx.doi.org/10.1167/iovs.64.4.34

Ejemplares similares