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TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition

BACKGROUND: The hepatitis B virus (HBV) vaccine has been efficiently used for decades. However, hepatocellular carcinoma caused by HBV is still prevalent globally. We previously reported that interferon (IFN)-induced tripartite motif-containing 25 (TRIM25) inhibited HBV replication by increasing the...

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Detalles Bibliográficos
Autores principales: Song, Hongxiao, Xiao, Qingfei, Xu, Fengchao, Wei, Qi, Wang, Fei, Tan, Guangyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150869/
https://www.ncbi.nlm.nih.gov/pubmed/36975005
http://dx.doi.org/10.1097/CM9.0000000000002617