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Atrophy signaling pathways in respiratory and limb muscles of guinea pigs exposed to chronic cigarette smoke: role of soluble guanylate cyclase stimulation

Skeletal muscle dysfunction in chronic obstructive pulmonary disease (COPD) is characterized by a significant reduction in muscle strength and endurance. Preclinical studies show that stimulation of the soluble guanylate cyclase (sGC)-cGMP pathway attenuates muscle mass loss and prevents cigarette s...

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Detalles Bibliográficos
Autores principales: Peinado, Víctor Ivo, Guitart, Maria, Blanco, Isabel, Tura-Ceide, Olga, Paul, Tanja, Barberà, Joan Albert, Barreiro, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151051/
https://www.ncbi.nlm.nih.gov/pubmed/36881560
http://dx.doi.org/10.1152/ajplung.00258.2022