Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol

The endocannabinoid 2-arachidonoylglycerol (2-AG) is an inflammatory mediator and ligand for the cannabinoid receptors CB1 and CB2. We investigated the atherogenic mechanisms set in motion by 2-AG. Therefore, we created two atherosclerotic mouse models with distinct cell-specific knockouts of the CB...

Descripción completa

Detalles Bibliográficos
Autores principales: Avraamidou, Elina, Nöthel, Moritz, Danisch, Melina, Bindila, Laura, Schmidt, Susanne V., Lutz, Beat, Nickenig, Georg, Jehle, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151305/
https://www.ncbi.nlm.nih.gov/pubmed/36178662
http://dx.doi.org/10.1007/s12265-022-10323-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151305/
https://www.ncbi.nlm.nih.gov/pubmed/36178662
http://dx.doi.org/10.1007/s12265-022-10323-z

Ejemplares similares