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Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol

The endocannabinoid 2-arachidonoylglycerol (2-AG) is an inflammatory mediator and ligand for the cannabinoid receptors CB1 and CB2. We investigated the atherogenic mechanisms set in motion by 2-AG. Therefore, we created two atherosclerotic mouse models with distinct cell-specific knockouts of the CB...

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Detalles Bibliográficos
Autores principales:	Avraamidou, Elina, Nöthel, Moritz, Danisch, Melina, Bindila, Laura, Schmidt, Susanne V., Lutz, Beat, Nickenig, Georg, Jehle, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10151305/ https://www.ncbi.nlm.nih.gov/pubmed/36178662 http://dx.doi.org/10.1007/s12265-022-10323-z

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